O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 S 17 2 19 0.109 0.465 View mutations
227 A 18 1 19 0.037 0.309 View mutations
228 M 8 11 19 0.621 0.531 View mutations
229 F 0 19 19 1.000 0.767 View mutations
230 E 17 2 19 0.134 0.492 View mutations
231 H 17 2 19 0.134 0.404 View mutations
232 E 18 1 19 0.107 0.412 View mutations
233 M 0 19 19 0.976 0.482 View mutations
234 E 10 9 19 0.514 0.446 View mutations
235 E 19 0 19 0.026 0.415 View mutations
236 S 19 0 19 0.001 0.372 View mutations
237 K 17 2 19 0.240 0.454 View mutations
238 K 15 4 19 0.267 0.512 View mutations
239 N 8 11 19 0.546 0.509 View mutations
240 R 19 0 19 0.042 0.516 View mutations
241 V 19 0 19 0.003 0.439 View mutations
242 E 19 0 19 0.058 0.435 View mutations
243 I 17 2 19 0.143 0.358 View mutations
244 N 19 0 19 0.001 0.417 View mutations
245 D 0 19 19 1.000 0.622 View mutations
246 V 3 16 19 0.830 0.528 View mutations
247 E 19 0 19 0.000 0.394 View mutations
248 P 18 1 19 0.139 0.462 View mutations
249 E 18 1 19 0.094 0.513 View mutations
250 V 14 5 19 0.247 0.485 View mutations