O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 V 19 0 19 0.068 0.471 View mutations
127 Q 5 14 19 0.665 0.535 View mutations
128 G 1 18 19 0.927 0.611 View mutations
129 K 18 1 19 0.052 0.467 View mutations
130 D 2 17 19 0.892 0.514 View mutations
131 W 0 19 19 1.000 0.588 View mutations
132 G 0 19 19 0.990 0.843 View mutations
133 F 6 13 19 0.619 0.578 View mutations
134 K 8 11 19 0.640 0.509 View mutations
135 K 19 0 19 0.025 0.397 View mutations
136 F 10 9 19 0.420 0.483 View mutations
137 I 2 17 19 0.854 0.773 View mutations
138 R 15 4 19 0.196 0.459 View mutations
139 R 14 5 19 0.281 0.396 View mutations
140 D 5 14 19 0.689 0.608 View mutations
141 F 15 4 19 0.242 0.485 View mutations
142 L 19 0 19 0.013 0.192 View mutations
143 L 19 0 19 0.000 0.412 View mutations
144 D 17 2 19 0.165 0.455 View mutations
145 E 19 0 19 0.000 0.497 View mutations
146 A 19 0 19 0.000 0.454 View mutations
147 N 11 8 19 0.400 0.436 View mutations
148 G 19 0 19 0.000 0.403 View mutations
149 L 19 0 19 0.046 0.286 View mutations
150 L 19 0 19 0.000 0.262 View mutations