O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 P 18 1 19 0.119 0.347 View mutations
152 D 4 15 19 0.816 0.571 View mutations
153 D 19 0 19 0.146 0.296 View mutations
154 K 18 1 19 0.044 0.379 View mutations
155 L 1 18 19 0.958 0.767 View mutations
156 T 19 0 19 0.001 0.441 View mutations
157 L 16 3 19 0.203 0.284 View mutations
158 F 18 1 19 0.090 0.477 View mutations
159 C 19 0 19 0.050 0.156 View mutations
160 E 19 0 19 0.004 0.397 View mutations
161 V 4 15 19 0.759 0.659 View mutations
162 S 6 13 19 0.683 0.540 View mutations
163 V 17 2 19 0.101 0.352 View mutations
164 V 17 2 19 0.166 0.442 View mutations
165 Q 19 0 19 0.001 0.371 View mutations
166 D 15 4 19 0.219 0.409 View mutations
167 S 19 0 19 0.000 0.353 View mutations
168 V 14 5 19 0.242 0.424 View mutations
169 N 19 0 19 0.001 0.400 View mutations
170 I 19 0 19 0.000 0.387 View mutations
171 S 16 3 19 0.215 0.412 View mutations
172 G 19 0 19 0.015 0.420 View mutations
173 Q 19 0 19 0.004 0.493 View mutations
174 N 19 0 19 0.002 0.500 View mutations
175 T 19 0 19 0.000 0.488 View mutations