O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 M 19 0 19 0.009 0.469 View mutations
177 N 19 0 19 0.002 0.433 View mutations
178 M 19 0 19 0.001 0.368 View mutations
179 V 19 0 19 0.061 0.417 View mutations
180 K 18 1 19 0.101 0.375 View mutations
181 V 19 0 19 0.003 0.328 View mutations
182 P 17 2 19 0.161 0.366 View mutations
183 E 19 0 19 0.020 0.463 View mutations
184 C 19 0 19 0.004 0.498 View mutations
185 R 19 0 19 0.000 0.580 View mutations
186 L 19 0 19 0.001 0.424 View mutations
187 A 18 1 19 0.095 0.477 View mutations
188 D 19 0 19 0.011 0.482 View mutations
189 E 14 5 19 0.254 0.389 View mutations
190 L 19 0 19 0.004 0.470 View mutations
191 G 18 1 19 0.067 0.471 View mutations
192 G 19 0 19 0.001 0.522 View mutations
193 L 12 7 19 0.368 0.482 View mutations
194 W 6 13 19 0.654 0.433 View mutations
195 E 18 1 19 0.038 0.376 View mutations
196 N 19 0 19 0.002 0.684 View mutations
197 S 19 0 19 0.006 0.489 View mutations
198 R 17 2 19 0.145 0.571 View mutations
199 F 12 7 19 0.425 0.494 View mutations
200 T 5 14 19 0.777 0.536 View mutations