O43791 (O43791)

Overview
Predicted structure (AF):
AF-O43791-F1-model_v4
Uniprot entry:
O43791
Gene:
O43791
Protein length:
374 residues
Mutations found:
7105
Benign based on D2Deep prediction:
5199 out of 7105 mutations
Pathogenic based on D2Deep prediction:
1906 out of 7105 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7105 mutations across 374 unique positions. There are 5199 benign and 1906 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 D 10 9 19 0.413 0.490 View mutations
202 C 18 1 19 0.040 0.453 View mutations
203 C 19 0 19 0.000 0.483 View mutations
204 L 19 0 19 0.000 0.483 View mutations
205 C 19 0 19 0.016 0.587 View mutations
206 V 7 12 19 0.578 0.441 View mutations
207 A 18 1 19 0.104 0.478 View mutations
208 G 19 0 19 0.077 0.463 View mutations
209 Q 17 2 19 0.102 0.469 View mutations
210 E 19 0 19 0.000 0.432 View mutations
211 F 12 7 19 0.404 0.481 View mutations
212 Q 5 14 19 0.716 0.439 View mutations
213 A 6 13 19 0.657 0.552 View mutations
214 H 9 10 19 0.564 0.526 View mutations
215 K 10 9 19 0.529 0.481 View mutations
216 A 1 18 19 0.913 0.760 View mutations
217 I 6 13 19 0.645 0.590 View mutations
218 L 0 19 19 0.996 0.865 View mutations
219 A 12 7 19 0.392 0.424 View mutations
220 A 19 0 19 0.003 0.286 View mutations
221 R 19 0 19 0.036 0.384 View mutations
222 S 1 18 19 0.889 0.807 View mutations
223 P 19 0 19 0.000 0.305 View mutations
224 V 7 12 19 0.623 0.581 View mutations
225 F 0 19 19 0.977 0.775 View mutations