O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 D 3 16 19 0.836 0.623 View mutations
77 F 0 19 19 1.000 0.917 View mutations
78 W 0 19 19 1.000 0.834 View mutations
79 R 1 18 19 0.948 0.750 View mutations
80 V 0 19 19 0.976 0.861 View mutations
81 L 0 19 19 1.000 1.000 View mutations
82 F 0 19 19 1.000 0.902 View mutations
83 K 0 19 19 1.000 0.810 View mutations
84 D 0 19 19 0.966 0.959 View mutations
85 Y 10 9 19 0.493 0.481 View mutations
86 N 11 8 19 0.455 0.456 View mutations
87 L 12 7 19 0.361 0.434 View mutations
88 E 14 5 19 0.272 0.352 View mutations
89 R 19 0 19 0.072 0.210 View mutations
90 Y 19 0 19 0.033 0.301 View mutations
91 G 19 0 19 0.006 0.380 View mutations
92 R 18 1 19 0.133 0.408 View mutations
93 L 11 8 19 0.405 0.455 View mutations
94 Q 19 0 19 0.037 0.379 View mutations
95 P 7 12 19 0.582 0.528 View mutations
96 I 9 10 19 0.559 0.511 View mutations
97 L 19 0 19 0.042 0.269 View mutations
98 D 19 0 19 0.014 0.296 View mutations
99 S 12 7 19 0.388 0.459 View mutations
100 F 17 2 19 0.151 0.293 View mutations