O43918 (O43918)

Overview
Predicted structure (AF):
AF-O43918-F1-model_v4
Uniprot entry:
O43918
Gene:
O43918
Protein length:
545 residues
Mutations found:
10354
Benign based on D2Deep prediction:
6550 out of 10354 mutations
Pathogenic based on D2Deep prediction:
3804 out of 10354 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 10354 mutations across 545 unique positions. There are 6550 benign and 3804 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
451 A 19 0 19 0.007 0.671 View mutations
452 A 14 5 19 0.273 0.557 View mutations
453 F 18 1 19 0.132 0.617 View mutations
454 H 19 0 19 0.000 0.637 View mutations
455 W 19 0 19 0.003 0.661 View mutations
456 R 12 7 19 0.384 0.504 View mutations
457 C 17 2 19 0.116 0.570 View mutations
458 H 19 0 19 0.004 0.647 View mutations
459 F 18 1 19 0.049 0.668 View mutations
460 P 19 0 19 0.000 0.687 View mutations
461 A 19 0 19 0.000 0.764 View mutations
462 G 19 0 19 0.000 0.756 View mutations
463 T 19 0 19 0.000 0.782 View mutations
464 S 19 0 19 0.001 0.815 View mutations
465 R 18 1 19 0.085 0.771 View mutations
466 P 19 0 19 0.029 0.762 View mutations
467 G 12 7 19 0.393 0.552 View mutations
468 T 19 0 19 0.013 0.860 View mutations
469 G 17 2 19 0.143 0.773 View mutations
470 L 19 0 19 0.042 0.761 View mutations
471 R 6 13 19 0.700 0.378 View mutations
472 C 19 0 19 0.002 0.602 View mutations
473 R 19 0 19 0.000 0.647 View mutations
474 S 19 0 19 0.000 0.585 View mutations
475 C 4 15 19 0.730 0.379 View mutations