O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 I 18 1 19 0.048 0.478 View mutations
27 K 19 0 19 0.013 0.492 View mutations
28 E 19 0 19 0.037 0.659 View mutations
29 K 18 1 19 0.083 0.674 View mutations
30 L 15 4 19 0.224 0.412 View mutations
31 I 13 6 19 0.331 0.482 View mutations
32 F 19 0 19 0.040 0.491 View mutations
33 P 0 19 19 0.979 0.645 View mutations
34 Y 18 1 19 0.061 0.429 View mutations
35 V 14 5 19 0.259 0.399 View mutations
36 E 19 0 19 0.001 0.497 View mutations
37 L 19 0 19 0.000 0.475 View mutations
38 D 15 4 19 0.263 0.567 View mutations
39 L 9 10 19 0.510 0.432 View mutations
40 H 19 0 19 0.077 0.606 View mutations
41 S 16 3 19 0.158 0.473 View mutations
42 Y 19 0 19 0.002 0.383 View mutations
43 D 19 0 19 0.000 0.375 View mutations
44 L 9 10 19 0.507 0.505 View mutations
45 G 2 17 19 0.895 0.458 View mutations
46 I 10 9 19 0.534 0.434 View mutations
47 E 18 1 19 0.133 0.580 View mutations
48 N 7 12 19 0.603 0.409 View mutations
49 R 0 19 19 0.997 0.662 View mutations
50 D 1 18 19 0.956 0.571 View mutations