O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 A 12 7 19 0.411 0.482 View mutations
52 T 0 19 19 0.988 0.618 View mutations
53 N 8 11 19 0.507 0.436 View mutations
54 D 9 10 19 0.508 0.509 View mutations
55 Q 17 2 19 0.104 0.587 View mutations
56 V 13 6 19 0.403 0.451 View mutations
57 T 0 19 19 1.000 0.695 View mutations
58 K 18 1 19 0.073 0.390 View mutations
59 D 18 1 19 0.053 0.510 View mutations
60 A 4 15 19 0.698 0.519 View mutations
61 A 3 16 19 0.835 0.619 View mutations
62 E 15 4 19 0.255 0.571 View mutations
63 A 19 0 19 0.056 0.444 View mutations
64 I 13 6 19 0.415 0.404 View mutations
65 K 18 1 19 0.098 0.483 View mutations
66 K 19 0 19 0.038 0.645 View mutations
67 H 14 5 19 0.292 0.458 View mutations
68 N 14 5 19 0.285 0.482 View mutations
69 V 18 1 19 0.173 0.225 View mutations
70 G 5 14 19 0.727 0.600 View mutations
71 V 1 18 19 0.945 0.754 View mutations
72 K 1 18 19 0.940 0.836 View mutations
73 C 0 19 19 1.000 0.864 View mutations
74 A 0 19 19 1.000 0.900 View mutations
75 T 0 19 19 0.995 0.957 View mutations