O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 S 0 19 19 0.988 0.790 View mutations
327 T 1 18 19 0.945 0.744 View mutations
328 N 3 16 19 0.868 0.646 View mutations
329 P 2 17 19 0.885 0.640 View mutations
330 I 1 18 19 0.948 0.671 View mutations
331 A 0 19 19 1.000 0.833 View mutations
332 S 0 19 19 1.000 0.759 View mutations
333 I 2 17 19 0.898 0.682 View mutations
334 F 0 19 19 0.978 0.617 View mutations
335 A 4 15 19 0.737 0.637 View mutations
336 W 9 10 19 0.457 0.513 View mutations
337 T 19 0 19 0.004 0.403 View mutations
338 R 12 7 19 0.366 0.419 View mutations
339 G 19 0 19 0.000 0.335 View mutations
340 L 1 18 19 0.954 0.632 View mutations
341 A 19 0 19 0.000 0.691 View mutations
342 H 18 1 19 0.092 0.489 View mutations
343 R 0 19 19 0.987 0.657 View mutations
344 A 2 17 19 0.915 0.456 View mutations
345 K 17 2 19 0.163 0.643 View mutations
346 L 8 11 19 0.499 0.514 View mutations
347 D 0 19 19 0.993 0.555 View mutations
348 N 15 4 19 0.200 0.576 View mutations
349 N 14 5 19 0.284 0.531 View mutations
350 K 19 0 19 0.003 0.738 View mutations