O75874 (O75874)

Overview
Predicted structure (AF):
AF-O75874-F1-model_v4
Uniprot entry:
O75874
Gene:
O75874
Protein length:
414 residues
Mutations found:
7865
Benign based on D2Deep prediction:
4621 out of 7865 mutations
Pathogenic based on D2Deep prediction:
3244 out of 7865 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 7865 mutations across 414 unique positions. There are 4621 benign and 3244 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 I 0 19 19 1.000 0.838 View mutations
77 T 1 18 19 0.927 0.755 View mutations
78 P 0 19 19 1.000 0.777 View mutations
79 D 2 17 19 0.880 0.590 View mutations
80 E 1 18 19 0.944 0.485 View mutations
81 K 10 9 19 0.458 0.464 View mutations
82 R 0 19 19 1.000 0.722 View mutations
83 V 0 19 19 0.970 0.637 View mutations
84 E 9 10 19 0.566 0.454 View mutations
85 E 0 19 19 0.985 0.496 View mutations
86 F 9 10 19 0.549 0.509 View mutations
87 K 9 10 19 0.494 0.448 View mutations
88 L 0 19 19 0.969 0.699 View mutations
89 K 19 0 19 0.019 0.442 View mutations
90 Q 19 0 19 0.000 0.518 View mutations
91 M 11 8 19 0.426 0.488 View mutations
92 W 19 0 19 0.002 0.376 View mutations
93 K 13 6 19 0.326 0.500 View mutations
94 S 15 4 19 0.256 0.346 View mutations
95 P 0 19 19 1.000 0.855 View mutations
96 N 0 19 19 1.000 0.805 View mutations
97 G 3 16 19 0.863 0.648 View mutations
98 T 0 19 19 0.908 0.762 View mutations
99 I 0 19 19 0.973 0.693 View mutations
100 R 0 19 19 0.995 0.656 View mutations