P01111 (NRAS)

Overview
Predicted structure (AF):
AF-P01111-F1-model_v4
Uniprot entry:
P01111
Gene:
NRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
2085 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1505 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3590 mutations across 189 unique positions. There are 2085 benign and 1505 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 E 2 17 19 0.929 0.538 View mutations
77 G 0 19 19 0.950 0.711 View mutations
78 F 0 19 19 1.000 0.666 View mutations
79 L 1 18 19 0.963 0.611 View mutations
80 C 1 18 19 0.944 0.541 View mutations
81 V 0 19 19 0.989 0.663 View mutations
82 F 0 19 19 0.997 0.533 View mutations
83 A 0 19 19 0.974 0.476 View mutations
84 I 19 0 19 0.046 0.372 View mutations
85 N 15 4 19 0.256 0.463 View mutations
86 N 18 1 19 0.035 0.453 View mutations
87 S 12 7 19 0.346 0.494 View mutations
88 K 19 0 19 0.003 0.593 View mutations
89 S 19 0 19 0.063 0.447 View mutations
90 F 19 0 19 0.000 0.451 View mutations
91 A 18 1 19 0.037 0.518 View mutations
92 D 19 0 19 0.001 0.598 View mutations
93 I 9 10 19 0.565 0.445 View mutations
94 N 19 0 19 0.001 0.688 View mutations
95 L 19 0 19 0.005 0.598 View mutations
96 Y 1 18 19 0.907 0.346 View mutations
97 R 19 0 19 0.011 0.549 View mutations
98 E 19 0 19 0.082 0.507 View mutations
99 Q 0 19 19 0.956 0.556 View mutations
100 I 0 19 19 1.000 0.664 View mutations