P01111 (NRAS)

Overview
Predicted structure (AF):
AF-P01111-F1-model_v4
Uniprot entry:
P01111
Gene:
NRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
2085 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1505 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3590 mutations across 189 unique positions. There are 2085 benign and 1505 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 K 19 0 19 0.001 0.470 View mutations
102 R 4 15 19 0.687 0.560 View mutations
103 V 1 18 19 0.943 0.693 View mutations
104 K 0 19 19 0.997 0.666 View mutations
105 D 0 19 19 0.967 0.515 View mutations
106 S 13 6 19 0.250 0.462 View mutations
107 D 19 0 19 0.003 0.384 View mutations
108 D 19 0 19 0.008 0.532 View mutations
109 V 19 0 19 0.014 0.356 View mutations
110 P 19 0 19 0.088 0.388 View mutations
111 M 14 5 19 0.271 0.408 View mutations
112 V 12 7 19 0.395 0.411 View mutations
113 L 19 0 19 0.038 0.427 View mutations
114 V 11 8 19 0.436 0.473 View mutations
115 G 0 19 19 0.967 0.637 View mutations
116 N 0 19 19 0.894 0.836 View mutations
117 K 0 19 19 0.999 0.688 View mutations
118 C 19 0 19 0.012 0.490 View mutations
119 D 2 17 19 0.885 0.714 View mutations
120 L 14 5 19 0.260 0.472 View mutations
121 P 14 5 19 0.298 0.473 View mutations
122 T 19 0 19 0.003 0.495 View mutations
123 R 11 8 19 0.465 0.499 View mutations
124 T 17 2 19 0.143 0.423 View mutations
125 V 2 17 19 0.877 0.531 View mutations