P01112 (HRAS)

Overview
Predicted structure (AF):
AF-P01112-F1-model_v4
Uniprot entry:
P01112
Gene:
HRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
1973 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1617 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3590 mutations across 189 unique positions. There are 1973 benign and 1617 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 C 2 17 19 0.894 0.405 View mutations
52 L 4 15 19 0.786 0.404 View mutations
53 L 0 19 19 1.000 0.628 View mutations
54 D 1 18 19 0.942 0.556 View mutations
55 I 19 0 19 0.007 0.292 View mutations
56 L 3 16 19 0.864 0.712 View mutations
57 D 0 19 19 1.000 0.830 View mutations
58 T 2 17 19 0.823 0.895 View mutations
59 A 1 18 19 0.915 0.849 View mutations
60 G 0 19 19 0.999 0.942 View mutations
61 Q 0 19 19 1.000 0.717 View mutations
62 E 0 19 19 1.000 0.724 View mutations
63 E 7 12 19 0.608 0.538 View mutations
64 Y 5 14 19 0.756 0.519 View mutations
65 S 4 15 19 0.791 0.519 View mutations
66 A 0 19 19 0.977 0.663 View mutations
67 M 1 18 19 0.934 0.553 View mutations
68 R 0 19 19 0.996 0.576 View mutations
69 D 15 4 19 0.240 0.454 View mutations
70 Q 12 7 19 0.418 0.471 View mutations
71 Y 1 18 19 0.967 0.589 View mutations
72 M 4 15 19 0.806 0.535 View mutations
73 R 0 19 19 0.985 0.599 View mutations
74 T 2 17 19 0.862 0.523 View mutations
75 G 0 19 19 0.941 0.638 View mutations