P01112 (HRAS)

Overview
Predicted structure (AF):
AF-P01112-F1-model_v4
Uniprot entry:
P01112
Gene:
HRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
1973 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1617 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3590 mutations across 189 unique positions. There are 1973 benign and 1617 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 N 12 7 19 0.332 0.494 View mutations
27 H 19 0 19 0.004 0.596 View mutations
28 F 13 6 19 0.412 0.443 View mutations
29 V 3 16 19 0.847 0.452 View mutations
30 D 6 13 19 0.654 0.437 View mutations
31 E 18 1 19 0.149 0.362 View mutations
32 Y 0 19 19 0.977 0.573 View mutations
33 D 0 19 19 1.000 0.580 View mutations
34 P 0 19 19 0.976 0.692 View mutations
35 T 0 19 19 1.000 0.705 View mutations
36 I 2 17 19 0.832 0.602 View mutations
37 E 3 16 19 0.766 0.549 View mutations
38 D 0 19 19 0.999 0.618 View mutations
39 S 0 19 19 1.000 0.566 View mutations
40 Y 1 18 19 0.951 0.506 View mutations
41 R 0 19 19 0.967 0.479 View mutations
42 K 5 14 19 0.711 0.522 View mutations
43 Q 19 0 19 0.000 0.466 View mutations
44 V 4 15 19 0.787 0.457 View mutations
45 V 4 15 19 0.782 0.412 View mutations
46 I 5 14 19 0.705 0.501 View mutations
47 D 10 9 19 0.479 0.428 View mutations
48 G 17 2 19 0.160 0.440 View mutations
49 E 6 13 19 0.613 0.414 View mutations
50 T 9 10 19 0.549 0.442 View mutations