P01112 (HRAS)

Overview
Predicted structure (AF):
AF-P01112-F1-model_v4
Uniprot entry:
P01112
Gene:
HRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
1973 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1617 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3590 mutations across 189 unique positions. There are 1973 benign and 1617 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 E 1 18 19 0.942 0.508 View mutations
77 G 0 19 19 0.969 0.673 View mutations
78 F 0 19 19 1.000 0.641 View mutations
79 L 0 19 19 0.981 0.594 View mutations
80 C 1 18 19 0.948 0.523 View mutations
81 V 0 19 19 0.997 0.640 View mutations
82 F 0 19 19 0.993 0.512 View mutations
83 A 0 19 19 0.976 0.456 View mutations
84 I 19 0 19 0.060 0.397 View mutations
85 N 4 15 19 0.766 0.404 View mutations
86 N 18 1 19 0.044 0.485 View mutations
87 T 14 5 19 0.272 0.546 View mutations
88 K 19 0 19 0.004 0.624 View mutations
89 S 19 0 19 0.045 0.479 View mutations
90 F 19 0 19 0.000 0.489 View mutations
91 E 19 0 19 0.002 0.559 View mutations
92 D 19 0 19 0.000 0.616 View mutations
93 I 6 13 19 0.595 0.400 View mutations
94 H 19 0 19 0.000 0.705 View mutations
95 Q 18 1 19 0.071 0.597 View mutations
96 Y 2 17 19 0.875 0.355 View mutations
97 R 18 1 19 0.048 0.554 View mutations
98 E 16 3 19 0.166 0.493 View mutations
99 Q 0 19 19 0.999 0.552 View mutations
100 I 0 19 19 1.000 0.637 View mutations