P01112 (HRAS)

Overview
Predicted structure (AF):
AF-P01112-F1-model_v4
Uniprot entry:
P01112
Gene:
HRAS
Protein length:
189 residues
Mutations found:
3590
Benign based on D2Deep prediction:
1973 out of 3590 mutations
Pathogenic based on D2Deep prediction:
1617 out of 3590 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3590 mutations across 189 unique positions. There are 1973 benign and 1617 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 K 19 0 19 0.013 0.487 View mutations
102 R 3 16 19 0.817 0.549 View mutations
103 V 1 18 19 0.957 0.669 View mutations
104 K 0 19 19 0.999 0.618 View mutations
105 D 1 18 19 0.970 0.478 View mutations
106 S 9 10 19 0.492 0.441 View mutations
107 D 19 0 19 0.032 0.425 View mutations
108 D 17 2 19 0.114 0.547 View mutations
109 V 18 1 19 0.036 0.405 View mutations
110 P 17 2 19 0.103 0.450 View mutations
111 M 12 7 19 0.333 0.432 View mutations
112 V 8 11 19 0.557 0.436 View mutations
113 L 19 0 19 0.023 0.439 View mutations
114 V 12 7 19 0.399 0.463 View mutations
115 G 1 18 19 0.948 0.604 View mutations
116 N 0 19 19 0.961 0.796 View mutations
117 K 0 19 19 0.999 0.645 View mutations
118 C 18 1 19 0.101 0.391 View mutations
119 D 2 17 19 0.877 0.678 View mutations
120 L 14 5 19 0.313 0.495 View mutations
121 A 14 5 19 0.302 0.492 View mutations
122 A 19 0 19 0.008 0.538 View mutations
123 R 2 17 19 0.846 0.468 View mutations
124 T 18 1 19 0.159 0.472 View mutations
125 V 2 17 19 0.892 0.506 View mutations