P01116-2 (KRAS)

Overview
Predicted structure (AF):
AF-P01116-2-F1-model_v4
Uniprot entry:
P01116-2
Gene:
KRAS
Protein length:
188 residues
Mutations found:
3571
Benign based on D2Deep prediction:
2136 out of 3571 mutations
Pathogenic based on D2Deep prediction:
1435 out of 3571 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 3571 mutations across 188 unique positions. There are 2136 benign and 1435 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 N 16 3 19 0.196 0.591 View mutations
27 H 19 0 19 0.003 0.673 View mutations
28 F 18 1 19 0.100 0.542 View mutations
29 V 4 15 19 0.741 0.422 View mutations
30 D 10 9 19 0.515 0.445 View mutations
31 E 18 1 19 0.090 0.423 View mutations
32 Y 1 18 19 0.938 0.526 View mutations
33 D 0 19 19 1.000 0.558 View mutations
34 P 2 17 19 0.880 0.664 View mutations
35 T 0 19 19 1.000 0.715 View mutations
36 I 4 15 19 0.782 0.565 View mutations
37 E 5 14 19 0.684 0.519 View mutations
38 D 0 19 19 0.978 0.582 View mutations
39 S 0 19 19 0.998 0.502 View mutations
40 Y 1 18 19 0.939 0.456 View mutations
41 R 1 18 19 0.875 0.425 View mutations
42 K 9 10 19 0.607 0.429 View mutations
43 Q 19 0 19 0.000 0.523 View mutations
44 V 7 12 19 0.583 0.436 View mutations
45 V 3 16 19 0.806 0.394 View mutations
46 I 8 11 19 0.588 0.436 View mutations
47 D 8 11 19 0.548 0.435 View mutations
48 G 17 2 19 0.177 0.474 View mutations
49 E 10 9 19 0.439 0.460 View mutations
50 T 8 11 19 0.587 0.430 View mutations