P01116-2 (KRAS)

Overview
Predicted structure (AF):
AF-P01116-2-F1-model_v4
Uniprot entry:
P01116-2
Gene:
KRAS
Protein length:
188 residues
Mutations found:
3571
Benign based on D2Deep prediction:
2136 out of 3571 mutations
Pathogenic based on D2Deep prediction:
1435 out of 3571 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3571 mutations across 188 unique positions. There are 2136 benign and 1435 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 E 2 17 19 0.899 0.476 View mutations
77 G 0 19 19 0.937 0.671 View mutations
78 F 0 19 19 1.000 0.597 View mutations
79 L 1 18 19 0.923 0.553 View mutations
80 C 1 18 19 0.948 0.479 View mutations
81 V 0 19 19 0.996 0.597 View mutations
82 F 0 19 19 0.988 0.486 View mutations
83 A 0 19 19 0.972 0.439 View mutations
84 I 19 0 19 0.024 0.419 View mutations
85 N 14 5 19 0.248 0.501 View mutations
86 N 19 0 19 0.002 0.539 View mutations
87 T 14 5 19 0.279 0.589 View mutations
88 K 18 1 19 0.039 0.661 View mutations
89 S 19 0 19 0.035 0.525 View mutations
90 F 19 0 19 0.000 0.546 View mutations
91 E 19 0 19 0.032 0.613 View mutations
92 D 19 0 19 0.000 0.700 View mutations
93 I 13 6 19 0.331 0.538 View mutations
94 H 19 0 19 0.000 0.758 View mutations
95 H 19 0 19 0.024 0.660 View mutations
96 Y 3 16 19 0.869 0.337 View mutations
97 R 18 1 19 0.046 0.572 View mutations
98 E 19 0 19 0.021 0.532 View mutations
99 Q 0 19 19 0.974 0.517 View mutations
100 I 0 19 19 1.000 0.635 View mutations