P01116-2 (KRAS)

Overview
Predicted structure (AF):
AF-P01116-2-F1-model_v4
Uniprot entry:
P01116-2
Gene:
KRAS
Protein length:
188 residues
Mutations found:
3571
Benign based on D2Deep prediction:
2136 out of 3571 mutations
Pathogenic based on D2Deep prediction:
1435 out of 3571 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 3571 mutations across 188 unique positions. There are 2136 benign and 1435 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 K 19 0 19 0.033 0.358 View mutations
102 R 8 11 19 0.573 0.509 View mutations
103 V 2 17 19 0.919 0.638 View mutations
104 K 0 19 19 0.960 0.601 View mutations
105 D 1 18 19 0.920 0.446 View mutations
106 S 13 6 19 0.283 0.500 View mutations
107 E 18 1 19 0.040 0.474 View mutations
108 D 19 0 19 0.003 0.606 View mutations
109 V 19 0 19 0.019 0.455 View mutations
110 P 18 1 19 0.056 0.461 View mutations
111 M 16 3 19 0.176 0.462 View mutations
112 V 16 3 19 0.253 0.424 View mutations
113 L 19 0 19 0.006 0.448 View mutations
114 V 10 9 19 0.465 0.493 View mutations
115 G 3 16 19 0.855 0.571 View mutations
116 N 1 18 19 0.903 0.787 View mutations
117 K 0 19 19 1.000 0.631 View mutations
118 C 19 0 19 0.016 0.445 View mutations
119 D 2 17 19 0.908 0.681 View mutations
120 L 16 3 19 0.201 0.490 View mutations
121 P 16 3 19 0.167 0.557 View mutations
122 S 19 0 19 0.003 0.583 View mutations
123 R 10 9 19 0.404 0.429 View mutations
124 T 17 2 19 0.104 0.488 View mutations
125 V 5 14 19 0.738 0.451 View mutations