P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
326 R 1 18 19 0.948 0.604 View mutations
327 G 1 18 19 0.953 0.676 View mutations
328 R 3 16 19 0.852 0.555 View mutations
329 W 1 18 19 0.912 0.644 View mutations
330 H 0 19 19 0.981 0.755 View mutations
331 G 0 19 19 1.000 0.831 View mutations
332 D 0 19 19 0.998 0.715 View mutations
333 V 0 19 19 0.996 0.753 View mutations
334 A 0 19 19 1.000 0.707 View mutations
335 V 1 18 19 0.947 0.601 View mutations
336 K 0 19 19 1.000 0.634 View mutations
337 V 3 16 19 0.827 0.566 View mutations
338 L 3 16 19 0.841 0.639 View mutations
339 K 16 3 19 0.165 0.412 View mutations
340 V 0 19 19 1.000 0.634 View mutations
341 S 3 16 19 0.836 0.519 View mutations
342 Q 5 14 19 0.747 0.524 View mutations
343 P 0 19 19 1.000 0.754 View mutations
344 T 0 19 19 1.000 0.661 View mutations
345 A 17 2 19 0.105 0.405 View mutations
346 E 8 11 19 0.593 0.520 View mutations
347 Q 0 19 19 1.000 0.785 View mutations
348 A 4 15 19 0.776 0.639 View mutations
349 Q 4 15 19 0.800 0.569 View mutations
350 A 0 19 19 1.000 0.833 View mutations