P10398 (P10398)

Overview
Predicted structure (AF):
AF-P10398-F1-model_v4
Uniprot entry:
P10398
Gene:
P10398
Protein length:
606 residues
Mutations found:
11513
Benign based on D2Deep prediction:
5653 out of 11513 mutations
Pathogenic based on D2Deep prediction:
5860 out of 11513 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Table results: 11513 mutations across 606 unique positions. There are 5653 benign and 5860 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
501 E 0 19 19 0.999 0.694 View mutations
502 L 0 19 19 1.000 0.641 View mutations
503 M 2 17 19 0.920 0.525 View mutations
504 T 0 19 19 1.000 0.547 View mutations
505 G 0 19 19 1.000 0.627 View mutations
506 S 6 13 19 0.647 0.506 View mutations
507 L 1 18 19 0.953 0.612 View mutations
508 P 0 19 19 1.000 0.680 View mutations
509 Y 1 18 19 0.956 0.667 View mutations
510 S 12 7 19 0.428 0.490 View mutations
511 H 3 16 19 0.825 0.537 View mutations
512 I 10 9 19 0.472 0.494 View mutations
513 G 19 0 19 0.000 0.413 View mutations
514 C 18 1 19 0.064 0.387 View mutations
515 R 1 18 19 0.948 0.659 View mutations
516 D 6 13 19 0.638 0.598 View mutations
517 Q 9 10 19 0.528 0.515 View mutations
518 I 0 19 19 0.987 0.771 View mutations
519 I 0 19 19 0.994 0.768 View mutations
520 F 2 17 19 0.895 0.633 View mutations
521 M 17 2 19 0.130 0.315 View mutations
522 V 0 19 19 0.998 0.709 View mutations
523 G 0 19 19 1.000 0.747 View mutations
524 R 7 12 19 0.618 0.545 View mutations
525 G 6 13 19 0.708 0.547 View mutations