P10747 (P10747)

Overview
Predicted structure (AF):
AF-P10747-F1-model_v4
Uniprot entry:
P10747
Gene:
P10747
Protein length:
220 residues
Mutations found:
4179
Benign based on D2Deep prediction:
2503 out of 4179 mutations
Pathogenic based on D2Deep prediction:
1676 out of 4179 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4179 mutations across 220 unique positions. There are 2503 benign and 1676 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 F 0 19 19 0.986 0.744 View mutations
52 R 1 18 19 0.925 0.687 View mutations
53 A 0 19 19 1.000 0.865 View mutations
54 S 15 4 19 0.221 0.349 View mutations
55 L 5 14 19 0.752 0.646 View mutations
56 H 9 10 19 0.575 0.510 View mutations
57 K 0 19 19 0.982 0.840 View mutations
58 G 0 19 19 0.998 0.771 View mutations
59 L 9 10 19 0.530 0.501 View mutations
60 D 14 5 19 0.334 0.473 View mutations
61 S 10 9 19 0.523 0.498 View mutations
62 A 1 18 19 0.943 0.529 View mutations
63 V 15 4 19 0.239 0.420 View mutations
64 E 12 7 19 0.406 0.483 View mutations
65 V 4 15 19 0.786 0.531 View mutations
66 C 0 19 19 1.000 0.620 View mutations
67 V 14 5 19 0.307 0.478 View mutations
68 V 10 9 19 0.446 0.441 View mutations
69 Y 18 1 19 0.107 0.590 View mutations
70 G 12 7 19 0.353 0.438 View mutations
71 N 14 5 19 0.393 0.478 View mutations
72 Y 15 4 19 0.235 0.625 View mutations
73 S 3 16 19 0.797 0.381 View mutations
74 Q 16 3 19 0.178 0.688 View mutations
75 Q 18 1 19 0.125 0.717 View mutations