P10747 (P10747)

Overview
Predicted structure (AF):
AF-P10747-F1-model_v4
Uniprot entry:
P10747
Gene:
P10747
Protein length:
220 residues
Mutations found:
4179
Benign based on D2Deep prediction:
2503 out of 4179 mutations
Pathogenic based on D2Deep prediction:
1676 out of 4179 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4179 mutations across 220 unique positions. There are 2503 benign and 1676 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 S 17 2 19 0.082 0.547 View mutations
27 P 1 18 19 0.863 0.473 View mutations
28 M 15 4 19 0.283 0.511 View mutations
29 L 13 6 19 0.400 0.448 View mutations
30 V 7 12 19 0.524 0.430 View mutations
31 A 17 2 19 0.104 0.491 View mutations
32 Y 16 3 19 0.229 0.602 View mutations
33 D 18 1 19 0.099 0.570 View mutations
34 N 19 0 19 0.037 0.536 View mutations
35 A 18 1 19 0.080 0.704 View mutations
36 V 19 0 19 0.033 0.446 View mutations
37 N 15 4 19 0.237 0.526 View mutations
38 L 0 19 19 0.908 0.663 View mutations
39 S 11 8 19 0.514 0.432 View mutations
40 C 0 19 19 0.999 0.658 View mutations
41 K 13 6 19 0.367 0.419 View mutations
42 Y 1 18 19 0.934 0.589 View mutations
43 S 18 1 19 0.031 0.451 View mutations
44 Y 8 11 19 0.564 0.436 View mutations
45 N 5 14 19 0.754 0.440 View mutations
46 L 15 4 19 0.276 0.459 View mutations
47 F 16 3 19 0.231 0.376 View mutations
48 S 16 3 19 0.188 0.454 View mutations
49 R 3 16 19 0.788 0.538 View mutations
50 E 0 19 19 0.990 0.701 View mutations