P10747 (P10747)

Overview
Predicted structure (AF):
AF-P10747-F1-model_v4
Uniprot entry:
P10747
Gene:
P10747
Protein length:
220 residues
Mutations found:
4179
Benign based on D2Deep prediction:
2503 out of 4179 mutations
Pathogenic based on D2Deep prediction:
1676 out of 4179 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4179 mutations across 220 unique positions. There are 2503 benign and 1676 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 L 9 10 19 0.494 0.453 View mutations
77 Q 17 2 19 0.116 0.596 View mutations
78 V 4 15 19 0.703 0.331 View mutations
79 Y 12 7 19 0.403 0.511 View mutations
80 S 5 14 19 0.710 0.416 View mutations
81 K 14 5 19 0.275 0.534 View mutations
82 T 7 12 19 0.567 0.416 View mutations
83 G 11 8 19 0.468 0.432 View mutations
84 F 19 0 19 0.023 0.485 View mutations
85 N 19 0 19 0.004 0.610 View mutations
86 C 0 19 19 0.958 0.587 View mutations
87 D 15 4 19 0.256 0.519 View mutations
88 G 16 3 19 0.170 0.394 View mutations
89 K 19 0 19 0.003 0.704 View mutations
90 L 19 0 19 0.067 0.462 View mutations
91 G 19 0 19 0.014 0.596 View mutations
92 N 19 0 19 0.000 0.488 View mutations
93 E 17 2 19 0.206 0.395 View mutations
94 S 19 0 19 0.036 0.470 View mutations
95 V 1 18 19 0.913 0.727 View mutations
96 T 10 9 19 0.404 0.451 View mutations
97 F 13 6 19 0.350 0.435 View mutations
98 Y 9 10 19 0.553 0.450 View mutations
99 L 15 4 19 0.251 0.402 View mutations
100 Q 13 6 19 0.288 0.517 View mutations