P10747 (P10747)

Overview
Predicted structure (AF):
AF-P10747-F1-model_v4
Uniprot entry:
P10747
Gene:
P10747
Protein length:
220 residues
Mutations found:
4179
Benign based on D2Deep prediction:
2503 out of 4179 mutations
Pathogenic based on D2Deep prediction:
1676 out of 4179 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4179 mutations across 220 unique positions. There are 2503 benign and 1676 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 E 6 13 19 0.664 0.584 View mutations
127 K 1 18 19 0.948 0.639 View mutations
128 S 0 19 19 0.978 0.728 View mutations
129 N 8 11 19 0.604 0.544 View mutations
130 G 0 19 19 1.000 0.926 View mutations
131 T 0 19 19 0.999 0.902 View mutations
132 I 4 15 19 0.722 0.645 View mutations
133 I 5 14 19 0.577 0.637 View mutations
134 H 2 17 19 0.779 0.623 View mutations
135 V 15 4 19 0.228 0.446 View mutations
136 K 18 1 19 0.091 0.433 View mutations
137 G 14 5 19 0.318 0.457 View mutations
138 K 18 1 19 0.035 0.762 View mutations
139 H 19 0 19 0.005 0.809 View mutations
140 L 18 1 19 0.073 0.806 View mutations
141 C 19 0 19 0.005 0.859 View mutations
142 P 19 0 19 0.000 0.930 View mutations
143 S 19 0 19 0.005 0.989 View mutations
144 P 17 2 19 0.094 0.895 View mutations
145 L 19 0 19 0.001 0.905 View mutations
146 F 19 0 19 0.005 0.914 View mutations
147 P 19 0 19 0.010 0.854 View mutations
148 G 19 0 19 0.000 0.807 View mutations
149 P 19 0 19 0.001 0.805 View mutations
150 S 19 0 19 0.000 0.849 View mutations