P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
201 F 2 17 19 0.876 0.666 View mutations
202 D 19 0 19 0.019 0.369 View mutations
203 G 19 0 19 0.000 0.276 View mutations
204 T 19 0 19 0.000 0.246 View mutations
205 R 6 13 19 0.669 0.579 View mutations
206 V 2 17 19 0.900 0.644 View mutations
207 Y 0 19 19 1.000 0.826 View mutations
208 S 2 17 19 0.892 0.661 View mutations
209 P 0 19 19 0.977 0.831 View mutations
210 P 18 1 19 0.057 0.238 View mutations
211 E 3 16 19 0.819 0.653 View mutations
212 W 2 17 19 0.927 0.623 View mutations
213 I 1 18 19 0.930 0.631 View mutations
214 R 4 15 19 0.741 0.406 View mutations
215 Y 17 2 19 0.121 0.450 View mutations
216 H 5 14 19 0.700 0.500 View mutations
217 R 9 10 19 0.523 0.432 View mutations
218 Y 3 16 19 0.824 0.644 View mutations
219 H 18 1 19 0.107 0.386 View mutations
220 G 19 0 19 0.001 0.377 View mutations
221 R 19 0 19 0.003 0.461 View mutations
222 S 8 11 19 0.602 0.514 View mutations
223 A 19 0 19 0.001 0.238 View mutations
224 A 8 11 19 0.579 0.531 View mutations
225 V 1 18 19 0.948 0.712 View mutations