P11309 (P11309)

Overview
Predicted structure (AF):
AF-P11309-F1-model_v4
Uniprot entry:
P11309
Gene:
P11309
Protein length:
313 residues
Mutations found:
5946
Benign based on D2Deep prediction:
3712 out of 5946 mutations
Pathogenic based on D2Deep prediction:
2234 out of 5946 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5946 mutations across 313 unique positions. There are 3712 benign and 2234 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 S 19 0 19 0.025 0.483 View mutations
102 G 14 5 19 0.378 0.466 View mutations
103 V 3 16 19 0.828 0.539 View mutations
104 I 1 18 19 0.958 0.649 View mutations
105 R 5 14 19 0.723 0.457 View mutations
106 L 12 7 19 0.367 0.475 View mutations
107 L 19 0 19 0.040 0.361 View mutations
108 D 3 16 19 0.846 0.564 View mutations
109 W 19 0 19 0.003 0.350 View mutations
110 F 19 0 19 0.000 0.422 View mutations
111 E 15 4 19 0.181 0.468 View mutations
112 R 18 1 19 0.075 0.494 View mutations
113 P 19 0 19 0.000 0.414 View mutations
114 D 18 1 19 0.108 0.448 View mutations
115 S 13 6 19 0.361 0.457 View mutations
116 F 16 3 19 0.248 0.399 View mutations
117 V 11 8 19 0.525 0.427 View mutations
118 L 19 0 19 0.025 0.424 View mutations
119 I 6 13 19 0.715 0.538 View mutations
120 L 13 6 19 0.310 0.472 View mutations
121 E 1 18 19 0.915 0.518 View mutations
122 R 16 3 19 0.126 0.482 View mutations
123 P 6 13 19 0.712 0.530 View mutations
124 E 16 3 19 0.208 0.405 View mutations
125 P 17 2 19 0.191 0.516 View mutations