P11487 (P11487)

Overview
Predicted structure (AF):
AF-P11487-F1-model_v4
Uniprot entry:
P11487
Gene:
P11487
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
1978 out of 4540 mutations
Pathogenic based on D2Deep prediction:
2562 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4540 mutations across 239 unique positions. There are 1978 benign and 2562 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 R 16 3 19 0.178 0.602 View mutations
27 R 19 0 19 0.089 0.638 View mutations
28 D 18 1 19 0.069 0.432 View mutations
29 A 3 16 19 0.775 0.421 View mutations
30 G 4 15 19 0.802 0.427 View mutations
31 G 1 18 19 0.902 0.516 View mutations
32 R 1 18 19 0.960 0.462 View mutations
33 G 0 19 19 1.000 0.579 View mutations
34 G 2 17 19 0.925 0.641 View mutations
35 V 0 19 19 1.000 0.738 View mutations
36 Y 1 18 19 0.945 0.667 View mutations
37 E 0 19 19 0.975 0.734 View mutations
38 H 0 19 19 1.000 0.690 View mutations
39 L 0 19 19 1.000 0.763 View mutations
40 G 0 19 19 1.000 0.752 View mutations
41 G 0 19 19 0.999 0.755 View mutations
42 A 13 6 19 0.415 0.434 View mutations
43 P 9 10 19 0.513 0.512 View mutations
44 R 0 19 19 1.000 0.671 View mutations
45 R 0 19 19 0.996 0.628 View mutations
46 R 0 19 19 1.000 0.772 View mutations
47 K 1 18 19 0.950 0.663 View mutations
48 L 0 19 19 0.999 0.734 View mutations
49 Y 0 19 19 1.000 0.717 View mutations
50 C 0 19 19 1.000 0.737 View mutations