P11487 (P11487)

Overview
Predicted structure (AF):
AF-P11487-F1-model_v4
Uniprot entry:
P11487
Gene:
P11487
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
1978 out of 4540 mutations
Pathogenic based on D2Deep prediction:
2562 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4540 mutations across 239 unique positions. There are 1978 benign and 2562 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 A 0 19 19 1.000 0.790 View mutations
52 T 0 19 19 1.000 0.771 View mutations
53 K 1 18 19 0.949 0.625 View mutations
54 Y 1 18 19 0.957 0.682 View mutations
55 H 4 15 19 0.774 0.637 View mutations
56 L 1 18 19 0.914 0.678 View mutations
57 Q 0 19 19 1.000 0.605 View mutations
58 L 2 17 19 0.898 0.573 View mutations
59 H 0 19 19 0.991 0.523 View mutations
60 P 4 15 19 0.773 0.458 View mutations
61 S 1 18 19 0.908 0.458 View mutations
62 G 0 19 19 1.000 0.598 View mutations
63 R 4 15 19 0.791 0.443 View mutations
64 V 1 18 19 0.958 0.546 View mutations
65 N 2 17 19 0.871 0.517 View mutations
66 G 0 19 19 0.990 0.612 View mutations
67 S 1 18 19 0.939 0.548 View mutations
68 L 0 19 19 0.980 0.531 View mutations
69 E 6 13 19 0.687 0.513 View mutations
70 N 7 12 19 0.615 0.437 View mutations
71 S 0 19 19 0.994 0.559 View mutations
72 A 3 16 19 0.800 0.543 View mutations
73 Y 1 18 19 0.951 0.584 View mutations
74 S 0 19 19 1.000 0.701 View mutations
75 I 2 17 19 0.910 0.663 View mutations