P11487 (P11487)

Overview
Predicted structure (AF):
AF-P11487-F1-model_v4
Uniprot entry:
P11487
Gene:
P11487
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
1978 out of 4540 mutations
Pathogenic based on D2Deep prediction:
2562 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4540 mutations across 239 unique positions. There are 1978 benign and 2562 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 L 0 19 19 0.988 0.714 View mutations
77 E 0 19 19 0.997 0.761 View mutations
78 I 0 19 19 0.999 0.793 View mutations
79 T 0 19 19 1.000 0.832 View mutations
80 A 0 19 19 1.000 0.905 View mutations
81 V 0 19 19 1.000 0.860 View mutations
82 E 1 18 19 0.949 0.815 View mutations
83 V 0 19 19 0.999 0.851 View mutations
84 G 0 19 19 1.000 0.902 View mutations
85 I 1 18 19 0.928 0.739 View mutations
86 V 1 18 19 0.931 0.877 View mutations
87 A 1 18 19 0.930 0.787 View mutations
88 I 4 15 19 0.800 0.690 View mutations
89 R 1 18 19 0.913 0.718 View mutations
90 G 0 19 19 0.984 0.837 View mutations
91 L 18 1 19 0.120 0.271 View mutations
92 F 10 9 19 0.474 0.485 View mutations
93 S 1 18 19 0.929 0.794 View mutations
94 G 4 15 19 0.748 0.665 View mutations
95 R 0 19 19 0.996 0.755 View mutations
96 Y 3 16 19 0.851 0.764 View mutations
97 L 3 16 19 0.826 0.756 View mutations
98 A 12 7 19 0.494 0.418 View mutations
99 M 13 6 19 0.407 0.386 View mutations
100 N 18 1 19 0.056 0.233 View mutations