P11487 (P11487)

Overview
Predicted structure (AF):
AF-P11487-F1-model_v4
Uniprot entry:
P11487
Gene:
P11487
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
1978 out of 4540 mutations
Pathogenic based on D2Deep prediction:
2562 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4540 mutations across 239 unique positions. There are 1978 benign and 2562 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 R 7 12 19 0.613 0.531 View mutations
152 L 1 18 19 0.969 0.653 View mutations
153 W 0 19 19 0.999 0.736 View mutations
154 Y 0 19 19 1.000 0.858 View mutations
155 V 0 19 19 0.999 0.837 View mutations
156 S 0 19 19 0.991 0.887 View mutations
157 V 1 18 19 0.946 0.899 View mutations
158 N 0 19 19 1.000 0.928 View mutations
159 G 0 19 19 1.000 0.927 View mutations
160 K 0 19 19 0.995 0.829 View mutations
161 G 0 19 19 1.000 0.928 View mutations
162 R 0 19 19 1.000 0.855 View mutations
163 P 0 19 19 1.000 1.000 View mutations
164 R 0 19 19 0.998 0.886 View mutations
165 R 1 18 19 0.931 0.791 View mutations
166 G 1 18 19 0.942 0.894 View mutations
167 F 7 12 19 0.603 0.589 View mutations
168 K 2 17 19 0.815 0.719 View mutations
169 T 13 6 19 0.332 0.356 View mutations
170 R 3 16 19 0.832 0.656 View mutations
171 R 0 19 19 0.997 0.751 View mutations
172 T 10 9 19 0.455 0.479 View mutations
173 Q 8 11 19 0.564 0.549 View mutations
174 K 1 18 19 0.910 0.795 View mutations
175 S 0 19 19 0.999 0.913 View mutations