P11487 (P11487)

Overview
Predicted structure (AF):
AF-P11487-F1-model_v4
Uniprot entry:
P11487
Gene:
P11487
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
1978 out of 4540 mutations
Pathogenic based on D2Deep prediction:
2562 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4540 mutations across 239 unique positions. There are 1978 benign and 2562 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 Y 0 19 19 0.990 0.875 View mutations
127 N 0 19 19 1.000 0.838 View mutations
128 T 0 19 19 1.000 0.857 View mutations
129 Y 0 19 19 1.000 0.787 View mutations
130 A 0 19 19 0.999 0.745 View mutations
131 S 0 19 19 1.000 0.684 View mutations
132 R 0 19 19 0.982 0.579 View mutations
133 L 8 11 19 0.596 0.436 View mutations
134 Y 1 18 19 0.948 0.470 View mutations
135 R 14 5 19 0.319 0.474 View mutations
136 T 15 4 19 0.183 0.494 View mutations
137 V 18 1 19 0.084 0.679 View mutations
138 S 16 3 19 0.170 0.621 View mutations
139 S 19 0 19 0.047 0.792 View mutations
140 T 18 1 19 0.092 0.777 View mutations
141 P 18 1 19 0.162 0.732 View mutations
142 G 17 2 19 0.096 0.698 View mutations
143 A 19 0 19 0.002 0.727 View mutations
144 R 18 1 19 0.069 0.672 View mutations
145 R 19 0 19 0.011 0.644 View mutations
146 Q 19 0 19 0.003 0.592 View mutations
147 P 15 4 19 0.165 0.493 View mutations
148 S 19 0 19 0.001 0.439 View mutations
149 A 17 2 19 0.109 0.450 View mutations
150 E 18 1 19 0.047 0.489 View mutations