P11912 (P11912)

Overview
Predicted structure (AF):
AF-P11912-F1-model_v4
Uniprot entry:
P11912
Gene:
P11912
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2752 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1541 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4293 mutations across 226 unique positions. There are 2752 benign and 1541 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 G 19 0 19 0.000 0.761 View mutations
102 G 18 1 19 0.114 0.634 View mutations
103 I 19 0 19 0.010 0.678 View mutations
104 Y 13 6 19 0.382 0.556 View mutations
105 V 12 7 19 0.368 0.590 View mutations
106 C 13 6 19 0.363 0.546 View mutations
107 R 19 0 19 0.005 0.847 View mutations
108 V 18 1 19 0.060 0.727 View mutations
109 Q 19 0 19 0.000 0.950 View mutations
110 E 13 6 19 0.376 75157894737.526 View mutations
111 G 19 0 19 0.005 0.940 View mutations
112 N 19 0 19 0.000 0.964 View mutations
113 E 19 0 19 0.001 0.974 View mutations
114 S 19 0 19 0.001 0.956 View mutations
115 Y 19 0 19 0.001 0.974 View mutations
116 Q 18 1 19 0.059 0.837 View mutations
117 Q 18 1 19 0.100 0.842 View mutations
118 S 19 0 19 0.011 0.792 View mutations
119 C 18 1 19 0.078 0.746 View mutations
120 G 19 0 19 0.002 0.609 View mutations
121 T 18 1 19 0.169 0.579 View mutations
122 Y 19 0 19 0.008 0.566 View mutations
123 L 0 19 19 0.959 0.366 View mutations
124 R 16 3 19 0.180 0.565 View mutations
125 V 1 18 19 0.881 0.321 View mutations