P11912 (P11912)

Overview
Predicted structure (AF):
AF-P11912-F1-model_v4
Uniprot entry:
P11912
Gene:
P11912
Protein length:
226 residues
Mutations found:
4293
Benign based on D2Deep prediction:
2752 out of 4293 mutations
Pathogenic based on D2Deep prediction:
1541 out of 4293 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4293 mutations across 226 unique positions. There are 2752 benign and 1541 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 R 19 0 19 0.043 0.709 View mutations
127 Q 10 9 19 0.501 0.474 View mutations
128 P 3 16 19 0.851 0.328 View mutations
129 P 13 6 19 0.252 0.545 View mutations
130 P 1 18 19 0.960 0.430 View mutations
131 R 2 17 19 0.866 0.397 View mutations
132 P 0 19 19 0.994 0.522 View mutations
133 F 0 19 19 0.993 0.549 View mutations
134 L 1 18 19 0.934 0.562 View mutations
135 D 8 11 19 0.606 0.510 View mutations
136 M 1 18 19 0.939 0.553 View mutations
137 G 1 18 19 0.908 0.572 View mutations
138 E 8 11 19 0.493 0.509 View mutations
139 G 17 2 19 0.104 0.418 View mutations
140 T 11 8 19 0.510 0.476 View mutations
141 K 0 19 19 0.958 0.615 View mutations
142 N 18 1 19 0.046 0.374 View mutations
143 R 19 0 19 0.035 0.444 View mutations
144 I 8 11 19 0.594 0.522 View mutations
145 I 12 7 19 0.422 0.467 View mutations
146 T 19 0 19 0.005 0.384 View mutations
147 A 5 14 19 0.690 0.551 View mutations
148 E 0 19 19 0.975 0.555 View mutations
149 G 9 10 19 0.467 0.509 View mutations
150 I 12 7 19 0.368 0.473 View mutations