P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 S 14 5 19 0.284 0.630 View mutations
27 T 16 3 19 0.170 0.662 View mutations
28 P 7 12 19 0.640 0.399 View mutations
29 E 2 17 19 0.846 0.382 View mutations
30 S 13 6 19 0.299 0.530 View mutations
31 G 12 7 19 0.390 0.492 View mutations
32 V 8 11 19 0.490 0.431 View mutations
33 F 3 16 19 0.824 0.395 View mutations
34 F 14 5 19 0.416 0.487 View mutations
35 P 11 8 19 0.462 0.488 View mutations
36 S 16 3 19 0.169 0.635 View mutations
37 G 4 15 19 0.686 0.382 View mutations
38 P 4 15 19 0.776 0.341 View mutations
39 E 1 18 19 0.915 0.350 View mutations
40 G 8 11 19 0.595 0.431 View mutations
41 L 2 17 19 0.867 0.331 View mutations
42 D 15 4 19 0.229 0.528 View mutations
43 A 18 1 19 0.062 0.855 View mutations
44 A 13 6 19 0.376 0.594 View mutations
45 A 3 16 19 0.809 0.257 View mutations
46 S 16 3 19 0.291 0.748 View mutations
47 S 19 0 19 0.109 0.854 View mutations
48 T 13 6 19 0.297 0.643 View mutations
49 A 4 15 19 0.766 0.245 View mutations
50 P 5 14 19 0.750 0.294 View mutations