P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 S 0 19 19 0.926 0.024 View mutations
52 T 6 13 19 0.654 0.316 View mutations
53 A 3 16 19 0.759 0.166 View mutations
54 T 5 14 19 0.687 0.276 View mutations
55 A 13 6 19 0.314 0.643 View mutations
56 A 12 7 19 0.393 0.596 View mutations
57 A 2 17 19 0.870 0.175 View mutations
58 A 3 16 19 0.799 0.234 View mutations
59 A 2 17 19 0.891 0.291 View mutations
60 L 1 18 19 0.938 0.370 View mutations
61 A 0 19 19 0.999 0.414 View mutations
62 Y 0 19 19 1.000 0.366 View mutations
63 Y 0 19 19 0.974 0.372 View mutations
64 R 3 16 19 0.845 0.410 View mutations
65 D 2 17 19 0.892 0.352 View mutations
66 A 12 7 19 0.354 0.493 View mutations
67 E 2 17 19 0.748 0.412 View mutations
68 A 10 9 19 0.481 0.444 View mutations
69 Y 9 10 19 0.491 0.437 View mutations
70 R 3 16 19 0.802 0.425 View mutations
71 H 5 14 19 0.715 0.443 View mutations
72 S 0 19 19 0.985 0.410 View mutations
73 P 1 18 19 0.949 0.506 View mutations
74 V 0 19 19 1.000 0.427 View mutations
75 F 0 19 19 0.999 0.402 View mutations