P15976 (GATA1)

Overview
Predicted structure (AF):
AF-P15976-F1-model_v4
Uniprot entry:
P15976
Gene:
GATA1
Protein length:
413 residues
Mutations found:
7846
Benign based on D2Deep prediction:
3634 out of 7846 mutations
Pathogenic based on D2Deep prediction:
4212 out of 7846 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 7846 mutations across 413 unique positions. There are 3634 benign and 4212 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 Q 0 19 19 0.999 0.313 View mutations
77 V 1 18 19 0.947 0.431 View mutations
78 Y 0 19 19 1.000 0.407 View mutations
79 P 0 19 19 0.999 0.553 View mutations
80 L 0 19 19 1.000 0.434 View mutations
81 L 0 19 19 1.000 0.388 View mutations
82 N 0 19 19 0.993 0.426 View mutations
83 C 1 18 19 0.870 0.376 View mutations
84 M 13 6 19 0.378 0.469 View mutations
85 E 8 11 19 0.574 0.437 View mutations
86 G 19 0 19 0.047 0.500 View mutations
87 I 19 0 19 0.019 0.415 View mutations
88 P 19 0 19 0.067 0.460 View mutations
89 G 19 0 19 0.003 0.509 View mutations
90 G 19 0 19 0.002 0.525 View mutations
91 S 19 0 19 0.003 0.514 View mutations
92 P 19 0 19 0.002 0.474 View mutations
93 Y 18 1 19 0.165 0.445 View mutations
94 A 18 1 19 0.090 0.536 View mutations
95 G 10 9 19 0.520 0.430 View mutations
96 W 4 15 19 0.625 0.411 View mutations
97 A 19 0 19 0.048 0.470 View mutations
98 Y 17 2 19 0.073 0.408 View mutations
99 G 18 1 19 0.140 0.500 View mutations
100 K 19 0 19 0.054 0.459 View mutations