P16403 (H1-2)

Overview
Predicted structure (AF):
AF-P16403-F1-model_v4
Uniprot entry:
P16403
Gene:
H1-2
Protein length:
213 residues
Mutations found:
4046
Benign based on D2Deep prediction:
2539 out of 4046 mutations
Pathogenic based on D2Deep prediction:
1507 out of 4046 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4046 mutations across 213 unique positions. There are 2539 benign and 1507 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 K 18 1 19 0.048 0.819 View mutations
27 K 19 0 19 0.012 0.882 View mutations
28 A 17 2 19 0.105 0.744 View mutations
29 G 19 0 19 0.012 0.790 View mutations
30 G 18 1 19 0.123 0.710 View mutations
31 T 17 2 19 0.070 0.690 View mutations
32 P 18 1 19 0.072 0.706 View mutations
33 R 9 10 19 0.527 0.450 View mutations
34 K 18 1 19 0.056 0.528 View mutations
35 A 7 12 19 0.574 0.424 View mutations
36 S 14 5 19 0.251 0.441 View mutations
37 G 5 14 19 0.658 0.539 View mutations
38 P 0 19 19 1.000 0.631 View mutations
39 P 2 17 19 0.900 0.516 View mutations
40 V 1 18 19 0.948 0.535 View mutations
41 S 1 18 19 0.953 0.535 View mutations
42 E 7 12 19 0.640 0.520 View mutations
43 L 16 3 19 0.168 0.421 View mutations
44 I 0 19 19 0.975 0.570 View mutations
45 T 0 19 19 0.994 0.549 View mutations
46 K 14 5 19 0.282 0.497 View mutations
47 A 3 16 19 0.828 0.576 View mutations
48 V 2 17 19 0.912 0.569 View mutations
49 A 4 15 19 0.777 0.559 View mutations
50 A 1 18 19 0.959 0.654 View mutations