P16403 (H1-2)

Overview
Predicted structure (AF):
AF-P16403-F1-model_v4
Uniprot entry:
P16403
Gene:
H1-2
Protein length:
213 residues
Mutations found:
4046
Benign based on D2Deep prediction:
2539 out of 4046 mutations
Pathogenic based on D2Deep prediction:
1507 out of 4046 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4046 mutations across 213 unique positions. There are 2539 benign and 1507 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 S 0 19 19 1.000 0.658 View mutations
52 K 0 19 19 1.000 0.618 View mutations
53 E 0 19 19 1.000 0.710 View mutations
54 R 0 19 19 0.988 0.611 View mutations
55 S 16 3 19 0.168 0.429 View mutations
56 G 0 19 19 0.998 0.753 View mutations
57 V 1 18 19 0.940 0.636 View mutations
58 S 5 14 19 0.736 0.615 View mutations
59 L 1 18 19 0.945 0.716 View mutations
60 A 0 19 19 0.984 0.767 View mutations
61 A 0 19 19 1.000 0.750 View mutations
62 L 0 19 19 1.000 0.737 View mutations
63 K 0 19 19 0.990 0.770 View mutations
64 K 0 19 19 0.991 0.804 View mutations
65 A 3 16 19 0.857 0.591 View mutations
66 L 0 19 19 0.998 0.778 View mutations
67 A 1 18 19 0.964 0.730 View mutations
68 A 0 19 19 0.997 0.780 View mutations
69 A 13 6 19 0.362 0.428 View mutations
70 G 0 19 19 0.968 0.953 View mutations
71 Y 0 19 19 1.000 0.942 View mutations
72 D 0 19 19 1.000 0.884 View mutations
73 V 0 19 19 1.000 0.963 View mutations
74 E 1 18 19 0.948 0.752 View mutations
75 K 0 19 19 0.999 0.739 View mutations