P16403 (H1-2)

Overview
Predicted structure (AF):
AF-P16403-F1-model_v4
Uniprot entry:
P16403
Gene:
H1-2
Protein length:
213 residues
Mutations found:
4046
Benign based on D2Deep prediction:
2539 out of 4046 mutations
Pathogenic based on D2Deep prediction:
1507 out of 4046 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4046 mutations across 213 unique positions. There are 2539 benign and 1507 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 N 1 18 19 0.957 0.790 View mutations
77 N 0 19 19 0.993 0.774 View mutations
78 S 0 19 19 1.000 0.753 View mutations
79 R 0 19 19 1.000 0.767 View mutations
80 I 0 19 19 0.984 0.751 View mutations
81 K 0 19 19 1.000 0.746 View mutations
82 L 0 19 19 0.999 0.688 View mutations
83 G 1 18 19 0.963 0.716 View mutations
84 L 3 16 19 0.781 0.684 View mutations
85 K 1 18 19 0.952 0.713 View mutations
86 S 12 7 19 0.398 0.458 View mutations
87 L 0 19 19 1.000 0.811 View mutations
88 V 0 19 19 1.000 0.882 View mutations
89 S 16 3 19 0.183 0.425 View mutations
90 K 14 5 19 0.338 0.415 View mutations
91 G 1 18 19 0.919 0.838 View mutations
92 T 19 0 19 0.000 0.238 View mutations
93 L 0 19 19 0.995 0.900 View mutations
94 V 7 12 19 0.640 0.566 View mutations
95 Q 0 19 19 1.000 0.819 View mutations
96 T 4 15 19 0.799 0.668 View mutations
97 K 3 16 19 0.790 0.712 View mutations
98 G 5 14 19 0.716 0.712 View mutations
99 T 4 15 19 0.749 0.664 View mutations
100 G 8 11 19 0.616 0.575 View mutations