P16403 (H1-2)

Overview
Predicted structure (AF):
AF-P16403-F1-model_v4
Uniprot entry:
P16403
Gene:
H1-2
Protein length:
213 residues
Mutations found:
4046
Benign based on D2Deep prediction:
2539 out of 4046 mutations
Pathogenic based on D2Deep prediction:
1507 out of 4046 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4046 mutations across 213 unique positions. There are 2539 benign and 1507 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 T 18 1 19 0.114 0.776 View mutations
127 K 11 8 19 0.472 0.529 View mutations
128 P 3 16 19 0.881 0.251 View mutations
129 K 19 0 19 0.052 0.823 View mutations
130 K 1 18 19 0.921 0.168 View mutations
131 P 14 5 19 0.325 0.669 View mutations
132 V 18 1 19 0.121 0.927 View mutations
133 G 16 3 19 0.149 0.833 View mutations
134 A 19 0 19 0.068 0.977 View mutations
135 A 19 0 19 0.002 1.000 View mutations
136 K 19 0 19 0.031 0.986 View mutations
137 K 17 2 19 0.124 0.875 View mutations
138 P 19 0 19 0.026 0.969 View mutations
139 K 19 0 19 0.088 0.980 View mutations
140 K 16 3 19 0.204 0.823 View mutations
141 A 19 0 19 0.006 0.990 View mutations
142 A 19 0 19 0.024 0.999 View mutations
143 G 18 1 19 0.074 0.936 View mutations
144 G 18 1 19 0.112 0.940 View mutations
145 A 19 0 19 0.012 0.945 View mutations
146 T 19 0 19 0.000 0.947 View mutations
147 P 14 5 19 0.245 0.709 View mutations
148 K 19 0 19 0.000 0.950 View mutations
149 K 19 0 19 0.004 0.935 View mutations
150 S 19 0 19 0.000 0.937 View mutations