P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
26 E 19 0 19 0.002 0.845 View mutations
27 C 19 0 19 0.003 0.788 View mutations
28 V 19 0 19 0.001 0.685 View mutations
29 C 9 10 19 0.493 0.459 View mutations
30 E 19 0 19 0.008 0.744 View mutations
31 N 19 0 19 0.001 0.700 View mutations
32 Y 19 0 19 0.016 0.712 View mutations
33 K 19 0 19 0.018 0.740 View mutations
34 L 19 0 19 0.009 0.755 View mutations
35 A 18 1 19 0.029 0.731 View mutations
36 V 19 0 19 0.004 0.820 View mutations
37 N 19 0 19 0.021 0.827 View mutations
38 C 17 2 19 0.138 0.681 View mutations
39 F 18 1 19 0.058 0.815 View mutations
40 V 17 2 19 0.087 0.700 View mutations
41 N 19 0 19 0.016 0.893 View mutations
42 N 19 0 19 0.015 0.799 View mutations
43 N 19 0 19 0.011 0.849 View mutations
44 R 18 1 19 0.084 0.720 View mutations
45 Q 17 2 19 0.103 0.729 View mutations
46 C 19 0 19 0.002 0.754 View mutations
47 Q 19 0 19 0.002 0.732 View mutations
48 C 19 0 19 0.015 0.649 View mutations
49 T 19 0 19 0.002 0.704 View mutations
50 S 18 1 19 0.068 0.703 View mutations