P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
51 V 12 7 19 0.310 0.509 View mutations
52 G 19 0 19 0.010 0.588 View mutations
53 A 17 2 19 0.144 0.652 View mutations
54 Q 19 0 19 0.003 0.753 View mutations
55 N 17 2 19 0.093 0.652 View mutations
56 T 18 1 19 0.043 0.671 View mutations
57 V 15 4 19 0.226 0.558 View mutations
58 I 19 0 19 0.004 0.701 View mutations
59 C 0 19 19 0.947 0.398 View mutations
60 S 12 7 19 0.324 0.481 View mutations
61 K 18 1 19 0.093 0.496 View mutations
62 L 9 10 19 0.533 0.501 View mutations
63 A 19 0 19 0.013 0.471 View mutations
64 A 19 0 19 0.033 0.464 View mutations
65 K 18 1 19 0.065 0.433 View mutations
66 C 0 19 19 0.995 0.658 View mutations
67 L 5 14 19 0.710 0.559 View mutations
68 V 9 10 19 0.462 0.504 View mutations
69 M 19 0 19 0.064 0.379 View mutations
70 K 14 5 19 0.268 0.458 View mutations
71 A 4 15 19 0.741 0.507 View mutations
72 E 16 3 19 0.142 0.494 View mutations
73 M 11 8 19 0.382 0.498 View mutations
74 N 19 0 19 0.062 0.567 View mutations
75 G 17 2 19 0.155 0.584 View mutations