P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
226 F 9 10 19 0.463 0.436 View mutations
227 H 19 0 19 0.015 0.660 View mutations
228 S 13 6 19 0.364 0.526 View mutations
229 K 7 12 19 0.621 0.413 View mutations
230 K 15 4 19 0.219 0.604 View mutations
231 M 5 14 19 0.723 0.417 View mutations
232 D 16 3 19 0.151 0.593 View mutations
233 L 3 16 19 0.887 0.429 View mutations
234 T 13 6 19 0.347 0.528 View mutations
235 V 14 5 19 0.289 0.470 View mutations
236 N 19 0 19 0.016 0.520 View mutations
237 G 2 17 19 0.847 0.437 View mutations
238 E 5 14 19 0.626 0.435 View mutations
239 Q 14 5 19 0.254 0.526 View mutations
240 L 14 5 19 0.257 0.413 View mutations
241 D 18 1 19 0.115 0.596 View mutations
242 L 11 8 19 0.473 0.500 View mutations
243 D 18 1 19 0.078 0.554 View mutations
244 P 18 1 19 0.038 0.513 View mutations
245 G 18 1 19 0.109 0.594 View mutations
246 Q 19 0 19 0.052 0.608 View mutations
247 T 17 2 19 0.097 0.388 View mutations
248 L 11 8 19 0.426 0.436 View mutations
249 I 1 18 19 0.899 0.562 View mutations
250 Y 3 16 19 0.817 0.574 View mutations