P16422 (EPCAM)

Overview
Predicted structure (AF):
AF-P16422-F1-model_v4
Uniprot entry:
P16422
Gene:
EPCAM
Protein length:
314 residues
Mutations found:
5965
Benign based on D2Deep prediction:
3951 out of 5965 mutations
Pathogenic based on D2Deep prediction:
2014 out of 5965 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 5965 mutations across 314 unique positions. There are 3951 benign and 2014 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 S 16 3 19 0.167 0.514 View mutations
77 K 18 1 19 0.067 0.492 View mutations
78 L 12 7 19 0.327 0.460 View mutations
79 G 9 10 19 0.545 0.437 View mutations
80 R 4 15 19 0.759 0.409 View mutations
81 R 18 1 19 0.118 0.497 View mutations
82 A 17 2 19 0.126 0.534 View mutations
83 K 13 6 19 0.332 0.453 View mutations
84 P 12 7 19 0.366 0.414 View mutations
85 E 19 0 19 0.006 0.385 View mutations
86 G 18 1 19 0.051 0.361 View mutations
87 A 8 11 19 0.466 0.518 View mutations
88 L 18 1 19 0.064 0.439 View mutations
89 Q 17 2 19 0.076 0.381 View mutations
90 N 18 1 19 0.037 0.379 View mutations
91 N 18 1 19 0.069 0.324 View mutations
92 D 19 0 19 0.027 0.293 View mutations
93 G 0 19 19 0.979 0.784 View mutations
94 L 12 7 19 0.387 0.441 View mutations
95 Y 0 19 19 0.998 0.748 View mutations
96 D 3 16 19 0.737 0.600 View mutations
97 P 0 19 19 0.979 0.785 View mutations
98 D 17 2 19 0.174 0.399 View mutations
99 C 0 19 19 0.946 0.662 View mutations
100 D 15 4 19 0.274 0.382 View mutations