P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
376 Y 1 18 19 0.937 0.812 View mutations
377 Y 4 15 19 0.783 0.673 View mutations
378 K 0 19 19 1.000 0.847 View mutations
379 L 0 19 19 0.985 0.929 View mutations
380 H 2 17 19 0.895 0.758 View mutations
381 N 3 16 19 0.866 0.717 View mutations
382 V 1 18 19 0.948 0.728 View mutations
383 N 0 19 19 0.979 0.780 View mutations
384 R 3 16 19 0.857 0.742 View mutations
385 P 2 17 19 0.861 0.798 View mutations
386 L 1 18 19 0.948 0.845 View mutations
387 T 0 19 19 0.990 0.849 View mutations
388 M 4 15 19 0.773 0.714 View mutations
389 K 1 18 19 0.928 0.791 View mutations
390 K 3 16 19 0.836 0.748 View mutations
391 E 7 12 19 0.510 0.627 View mutations
392 G 5 14 19 0.707 0.723 View mutations
393 I 1 18 19 0.878 0.915 View mutations
394 Q 12 7 19 0.411 0.398 View mutations
395 T 17 2 19 0.097 0.211 View mutations
396 R 13 6 19 0.300 0.377 View mutations
397 N 8 11 19 0.515 0.550 View mutations
398 R 1 18 19 0.893 0.755 View mutations
399 K 19 0 19 0.000 0.244 View mutations
400 M 4 15 19 0.755 0.644 View mutations