P23769 (GATA2)

Overview
Predicted structure (AF):
AF-P23769-F1-model_v4
Uniprot entry:
P23769
Gene:
GATA2
Protein length:
480 residues
Mutations found:
9119
Benign based on D2Deep prediction:
4824 out of 9119 mutations
Pathogenic based on D2Deep prediction:
4295 out of 9119 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 9119 mutations across 480 unique positions. There are 4824 benign and 4295 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 G 19 0 19 0.000 0.385 View mutations
102 K 19 0 19 0.003 0.374 View mutations
103 A 17 2 19 0.091 0.555 View mutations
104 A 11 8 19 0.430 0.488 View mutations
105 L 10 9 19 0.519 0.472 View mutations
106 S 19 0 19 0.061 0.635 View mutations
107 A 19 0 19 0.015 0.813 View mutations
108 A 19 0 19 0.002 0.842 View mutations
109 A 19 0 19 0.000 0.822 View mutations
110 A 19 0 19 0.000 0.751 View mutations
111 H 19 0 19 0.026 0.693 View mutations
112 H 19 0 19 0.020 0.705 View mutations
113 H 19 0 19 0.000 0.576 View mutations
114 N 18 1 19 0.075 0.467 View mutations
115 P 13 6 19 0.355 0.416 View mutations
116 W 18 1 19 0.128 0.498 View mutations
117 T 6 13 19 0.605 0.442 View mutations
118 V 19 0 19 0.031 0.367 View mutations
119 S 18 1 19 0.087 0.474 View mutations
120 P 18 1 19 0.099 0.399 View mutations
121 F 2 17 19 0.910 0.452 View mutations
122 S 14 5 19 0.229 0.468 View mutations
123 K 0 19 19 0.993 0.486 View mutations
124 T 6 13 19 0.679 0.415 View mutations
125 P 4 15 19 0.800 0.393 View mutations