P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
351 I 1 18 19 0.947 0.554 View mutations
352 N 1 18 19 0.966 0.649 View mutations
353 R 0 19 19 1.000 0.654 View mutations
354 P 0 19 19 1.000 0.745 View mutations
355 L 1 18 19 0.947 0.709 View mutations
356 T 3 16 19 0.788 0.683 View mutations
357 M 1 18 19 0.937 0.757 View mutations
358 K 0 19 19 0.999 0.737 View mutations
359 K 0 19 19 1.000 0.746 View mutations
360 E 1 18 19 0.940 0.835 View mutations
361 G 1 18 19 0.957 0.841 View mutations
362 I 0 19 19 0.999 0.861 View mutations
363 Q 0 19 19 1.000 0.760 View mutations
364 T 0 19 19 1.000 0.802 View mutations
365 R 0 19 19 0.998 0.790 View mutations
366 N 0 19 19 0.999 0.774 View mutations
367 R 0 19 19 0.998 0.738 View mutations
368 K 0 19 19 1.000 0.751 View mutations
369 M 3 16 19 0.828 0.656 View mutations
370 S 9 10 19 0.468 0.505 View mutations
371 S 10 9 19 0.476 0.494 View mutations
372 K 8 11 19 0.589 0.511 View mutations
373 S 1 18 19 0.945 0.504 View mutations
374 K 7 12 19 0.620 0.443 View mutations
375 K 1 18 19 0.919 0.405 View mutations