P23771-2 (GATA3)

Overview
Predicted structure (AF):
AF-P23771-2-F1-model_v4
Uniprot entry:
P23771-2
Gene:
GATA3
Protein length:
444 residues
Mutations found:
8435
Benign based on D2Deep prediction:
3875 out of 8435 mutations
Pathogenic based on D2Deep prediction:
4560 out of 8435 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 8435 mutations across 444 unique positions. There are 3875 benign and 4560 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 P 3 16 19 0.838 0.299 View mutations
77 P 9 10 19 0.475 0.454 View mutations
78 T 5 14 19 0.767 0.341 View mutations
79 H 7 12 19 0.612 0.400 View mutations
80 H 7 12 19 0.684 0.394 View mutations
81 G 2 17 19 0.812 0.307 View mutations
82 S 7 12 19 0.625 0.406 View mutations
83 Q 10 9 19 0.463 0.458 View mutations
84 V 18 1 19 0.062 0.440 View mutations
85 C 10 9 19 0.550 0.452 View mutations
86 R 18 1 19 0.049 0.494 View mutations
87 P 3 16 19 0.854 0.456 View mutations
88 P 15 4 19 0.248 0.558 View mutations
89 L 18 1 19 0.087 0.517 View mutations
90 L 19 0 19 0.042 0.545 View mutations
91 H 19 0 19 0.033 0.606 View mutations
92 G 19 0 19 0.000 0.588 View mutations
93 S 16 3 19 0.252 0.522 View mutations
94 L 11 8 19 0.386 0.469 View mutations
95 P 6 13 19 0.663 0.430 View mutations
96 W 12 7 19 0.338 0.408 View mutations
97 L 18 1 19 0.134 0.387 View mutations
98 D 18 1 19 0.148 0.378 View mutations
99 G 10 9 19 0.526 0.447 View mutations
100 G 9 10 19 0.527 0.437 View mutations